CPF Funded Research (1989 to present)
Year	Type*	Name	Institution	Title
2012	Junior Investigator	Jamie Ong	University of Toronto	Identification and characterization of FGFR2 isoforms in the midface of Crouzon syndrome mouse model
	Junior Investigator	Trish Elizabeth Parsons	University of Pittsburgh	Effects of acute hypoxia on development of craniofacial shape and cleft lip/palate
	Etiology	Rolf Stottmann	Cincinnati Children’s Hospital	Mechanism of craniofacial defects in Ttc21b null mice
	Cleft/Craniofacial	James Cray, Jr.	Georgia Health Sciences University	Effects of thyroxine on the craniosynostotic phenotype
	Children’s Craniofacial	Adriane Baylis	Nationwide Children’s Hospital	A language environmental analysis (LENA) of vocalizations of infants with cleft palate
Year	Type*	Name	Institution	Title
2011	Junior Investigator	Carrie Gotzke	University of Alberta	Development and Evaluation of the Speech Intelligibility Probe for Children with Cleft Palate Version 5
Year	Type*	Name	Institution	Title
2010	Junior Investigator	James Cray, Jr.	University of Pittsburgh	Rescue of Coronal Suture Fusion Using Relaxin in Rabbits with Delayed Onset Craniosynostosis
	Junior Investigator	Darren Smith	University of Pittsburgh	Bioprinting Customized 3D Tissue Engineered Bone Constructs.
	Etiology	Daniela Luquetti	University of Washington	Further Exploration in Microtia Etiology: Candidate Gene Analysis in a South American Population.
	Cleft/Craniofacial	Arin K. Greene	Children’s Hospital Boston	Biomechanical Evaluation of Particulate Bone Versus Bone Morphogenetic Protein (BMP) Following Inlay Cranioplasty.
Year	Type*	Name	Institution	Title
2009	Junior Investigator	Michael R. Bykowski	University of Pittsburgh	Inkjet-based bio-patterning to spatially control osteo- and angiogenesis
	Junior Investigator	Clifford Thomas Pereira	UCLA	Osteo-inductive effects of oxysterols on 2-dimensional and 3-dimensional human stem cell cultures
	Etiology	Antonio Planchart	Mount Desert Island Biological Laboratory	Is Foxq1b a mediator of the teratogenic effects of dioxin on jaw development?
	Cleft/Craniofacial	Licia Selleri	Cornell University Medical College	Rescue of cleft lip/palate in Pbx mutant mice by restoring Wnt signaling
	Children’s Craniofacial	Arin K. Greene	Harvard University	Cranial Particulate Graft vs. Bone Dust for Inlay Cranioplasty
Year	Type*	Name	Institution	Title
2008	Junior Investigator	Seth M. Weinberg, PhD	University of Iowa	Pilot Study of Brain Structure and Function in Unaffected Relatives of Individuals with Nonsyndromic Orofacial Clefts
	Etiology	Roopa Purushothaman,BDS	University of Washington	The Developmental Role of Neural Crest in the Midfacial Phenotype of Apert Syndrome
	Cleft/Craniofacial	Partha Mukhopadhyay, PhD	University of Louisville School of Dentistry	BMP Regulated Transcription in Embryonic Palatal Tissue
	Children’s Craniofacial	Arin K. Greene, MD, MMSc	Harvard Medical School	Determining the Effectiveness of Autologous Calvarial Particulate Bone Graft for Onlay Cranioplasty
Year	Type*	Name	Institution	Title
2007	Junior Investigator	Josine Christine Collette Widdershoven, MSc	Utrecht University, The Netherlands	Whole genome association study of palatal abnormalities in 22q11.2 deletion syndrome
	Etiology	Vasker Bhattachergee, PhD	University of Louisville School of Dentistry	Chemokine-mediated migration of craniofacial neural crest cells
	Cleft/Craniofacial	L. Bruno Ruest, PhD	Baylor College of Dentistry	Early patterning genes of upper jaw development
	Children’s Craniofacial	Hiromi Yanagisawa, MD, PhD	University of Texas Southwestern	Molecular analysis of Tbx1-mediated pathway in palatal development
Year	Type*	Name	Institution	Title
2006	Junior Investigator	Adriane Baylis, MA	University of Minnesota	The Effect of Auditory Biofeedback on the Reduction of Nasal Air Emission in Speakers with Cleft Palate
	Etiology	Dennis R. Warner, PhD	University of Louisville	Gene Discovery in Embryonic Orofacial Tissue
	Cleft/Craniofacial	Joseph Losee, MD	Children’s Hospital of Pittsburgh	Repair of Craniofacial Defects with Adipose-Derived Stem Cells Co- Cultured With Infant Dura
	Children’s Craniofacial	Ryan Spivak, MS	Children’s Hospital of Philadelphia	In Utero Gene Delivery for Rescue of Cleft Palate in a Tgf-Beta 3 Knockout Mouse
Year	Type*	Name	Institution	Title
2005	Junior Investigator	Chad Perlyn, MD	Washington University, St. Louis	Etiology of Congenital Anomalies of the Trachea in Individuals withFGFR Mutations: Studies from a Crouzen Mouse Model
	Etiology	Yang Chai, DDS, PhD	University of Southern Cal-Los Angeles	Molecular Mechanism of Cleft Palate
	Cleft/Craniofacial	Liu Hong, MD, PhD	University of Illinois at Chicago	Sustaining Release of TGF-b3 for Inhibiting Induced Osseous Fusion of Rabbit Coronal Sutures
	Children’s Craniofacial	Joseph Losee, MD, FACS	Children’s Hospital of Pittsburgh	Noggin Gene-Based Therapy for Craniosynostosis
2004	Junior Investigator	Deonne Malick, MA	University of Iowa	Effects of Oral Pressure Modulation on Velopharyngeal Closure Force
	Etiology	Trevor Williams, PhD	University of Colorado-Denver	Analysis of Mechanisms of Orofacial Clefting in New Model, AP-2beta NN Mouse
	Cleft/Craniofacial	Richard Kirschner, MD	Children’s Hospital Philadelphia	Influence of Tensile Strain on Dural Cells and Cranial Sutures
	Children’s Craniofacial	Rebecca Gaither, PhD	Cleft Lip and Palate Institute-Illinois	Neurocognitive Outcomes in 8 to 12 Year Old Children with Craniosynostosis
2003	Junior Investigator	Devra Becker, MD	Washington University	Long-Term Clinical Outcome of Surgically Corrected Craniosynostosis
	Etiology	Vesa Kaartinen, PhD	Children’s Hospital Los Angeles	TGF-Beta Type I Receptor Alk2 in Craniofacial Development
	Children’s Craniofacial	Ines Chi-Ying Lin, BS, BA	Children’s Hospital Philadelphia	Role of Nitric Oxide in Fetal Craniofacial Development
	Cleft/Craniofacial	Judith Kusek,DDS, PhD	Baylor College of Dentistry	Expression and Function of the Notch Signaling Pathway During Pathogenesis
2002	Junior Investigator	Samson Lee, MD	University of Washington	Differential Gene Expression of Craniosynostosis
	Etiology	Diego Wyszynski, MD, PhD	Boston University	Genetic Dissection of Nonsyndromic Cleft Lip and Palate in a Middle Eastern Population
	Cleft/Craniofacial	Richard Spritz, MD	University of Colorado-Denver	PVRL1 Mutations in Patients with Nonsyndromic Cleft Lip and Palate
2001	Junior Investigator	Rodney Schmelzer, MD	St. Louis Children’s Hospital	Comparison of Effects on Endocranial Base for Two Surgical Approaches for Sagittal Craniosynostosis
	Etiology	Richard Kirschner, MD	Children’s Hospital Philadelphia	Toward Understanding Non-Syndromic Craniosynostosis: Role of Androgens in Craniofacial Development
	Cleft/Craniofacial	David Clouthier, PhD	University of Louisville	Developmental Control of Gene Expression by Endothelin Signaling
	Smile Train	Christos Katsaros, DDS, PhD	University of Nijmegen-Netherlands	Cytokine Expression During Intra-Oral Wound healing in a Dog Model
2000	Junior Investigator	Lonnie Zwaigenbaum, MD	Hamilton Health Sciences-Ontario	Psychiatric Disorder in Children With Cleft Palate and 22q11 Deletion Syndrome
	Cleft/Craniofacial	Joseph H. Shin, MD	Yale University	Strain Dependent Control of TGF-B Function in Bone Cells: A Model for Distraction Osteogenesis
	Smile Train	Nuno Hermann,DDS	University of Copenhagen-Denmark	Comparison of 3D Maxillary Shape Different Treatment Regimes of Clefts: Effect of Infant Orthopedics
1999	Junior Investigator	Geoffrey Guttmann, PhD	University of Saskatchewan	3D CT Analysis of Anterior Maxillary Clefts
	Etiology	Barzin Mobasher, PhD	Arizona State University	Finite Element Analysis of Deformation of the Infant Cranium in Deformational Plagiocephaly
	Cleft/Craniofacial	Siew-Ging Gong,BDS, PhD	University of Michigan	Molecular Characterization of the Twirler Mice
	Smile Train	Heather Beveridge, MSW	Hospital for Sick Children-Toronto	Evaluating the Effectiveness of Improvisational Acting on the Social Competence of Adolescents with Clefts
1998	Junior Investigator	James Mah,DDS, MSc, DMSc	Boston Children’s Hospital	Efficacy of FDA-Approved Bone Implant Materials
	Junior Investigator	Andrew Lidral,DDS, PhD	Ohio State University	Genetic Analysis of Cleft Palate Families in a Chinese Population
	Etiology	Robert M. Greene, PhD	University of Louisville	Etiology of Retionic Acid-Induced Cleft Palate
	Cleft/Craniofacial	Richard Kirschner, MD	Children’s Hospital Philadelphia	Pathobiology of Craniosynostosis: Role of Intrauterine Constraint
1997	Junior Investigator	Kathleen Russell, DDS, MSc	Dalhousie University-Nova Scotia	Analysis of the Influence of Presurgical Infant Orthopedics on Nasal Morphology
	Cleft/Craniofacial	Jason B. Cope,DDS	Texas A&M/Baylor College of Dentistry	Characterization of Late Stages in Membrane Bone Formation Following Distraction of the Mandible
1996	Junior Investigator	Wayne Ozaki, MD, DDS	University of Michigan	Bone Healing/Remodeling in Distraction Osteogenesis: Comparing Membranous & Endochondral Bone
	Etiology	Kang Ting, DMD,DMSc	University of California-Los Angeles	Sutural Closure Mechanisms in Craniosynostosis
	Cleft/Craniofacial	Eric A. Wulfsberg, MD	University of Maryland	Genetic Studies of the Acrofacial Dysostosis Syndromes
1995	Junior Investigator	James Bradley, MD	New York University	Investigation of Biology of Cranial Suture Fusion Using Chemically Defined Serum-Free Organ Culture
	Etiology	James Hartsfield, DMD, PhD	Indiana University	A Study of Genetic Non-Penetrance in Crouzon Syndrome
	Cleft/Craniofacial	Mark P. Mooney, PhD	University of Pittsburgh	Coronal Suture Transplant in Rabbits with Congenital Craniosynostosis
1994	Junior Investigator	Suzanne Krueckeberg, PhD	University of Illinois-Chicago	Longitudinal Follow-Up on Impact of Child & Parent Factors on Social Skills of Children with Craniofacial Anomalies
	Etiology	Harriet Oster, PhD	New York University	The Effects of Cleft and Craniofacial Anomalies on Infant Facial Expression and Mother Infant Interaction
	Cleft/Craniofacial	Jeffrey C. Posnick, DMD, MD	Georgtown University	School-Based Study: Social Perceptions of Osteotomies Reconstructing Congenital Midface Deformities
1993	Junior Investigator	John Canady, MD	University of Iowa	Cleft Palate Repair in a Fetal Ovine Model
	Etiology	Don LaRossa, MD	Children’s Hospital Philadelphia	Prevalence of 22q11 Microdeletions in Patients with Cleft Palate
	CLP	David Dean, PhD	New York University	Surface-Based Cephalometry: Diagnosis and Surgical Planning
1992	Etiology	Jacqueline T. Hecht, PhD	University of Texas-Houston	Linkage Study in Nonsyndromic Cleft Lip and Palate
	Cleft/Craniofacial	Nicholas Germane, DMD, MS	Medical College of Georgia	Alveolar Grafting with Demineralized Bone Powder from Cranial & Long Bone Origins in Animal Model
1991	Junior Investigator	Paul Green,DDS	Indiana University	Lip Prints as Microform of Cleft Lip and Palate
	Etiology	Carol Ballew, PhD	Illinois Cancer Council	Genetic Epidemiology of Cleft Lip and Palate in a Population Isolate
	Cleft/Craniofacial	Robert A. Hardesty, MD	Loma Linda University	Intrauterine Cleft Lip Repair in the Mouse: A Preamble to Prenatal Endoscopic Surgery
1990	Junior Investigator	David J. Zajac, PhD	University of Pittsburgh	An Aerodynamic and Kinematic Study of Vocal Function in Cleft Lip and Palate
1989	Junior Investigator	Linda A. Hallman, DDS, PhD	Thomas Jefferson University	Unrepaired Cleft Palate
Grant Type and Funding Sources
*	Junior Investigator	Funded by Peer Foundation, Florham Park, New Jersey (1989 to 2007); Funded by the Cleft Palate Foundation (2008 to 2011); Funded by Synthes and the Cleft Palate Foundation (2012 to present)
	Etiology Grant	Funded by Peer Foundation, Florham Park, New Jersey (1991 to 2008); Funded by the Cleft Palate Foundation (2009 to present)
	Cleft/Craniofacial	Funded by the American Association of Oral and Maxillofacial Surgeons, Rosemont, Illinois (1991 to present)
	Children’s Craniofacial	Funded by the Children’s Craniofacial Association (CCA), Dallas, Texas (2003 to 2008); Funded by CCA and the Cleft Palate Foundation (2009 to 2012)
	Smile Train	Funded by The Smile Train, New York, New York (1999-2001)